Propofol (Injectable emulsion)
Propofol is used to induce and maintain sleep during anesthesia used during surgery in adults and children 3 years of age and older. It can be used for adults before a medical procedure that can cause discomfort to relax and reduce sensitivity, but without inducing sleep.
What is propofol?
Propofol belongs to the class of medications called hypnotics or anesthetics. Hypnotics cause sleep and reduce sensitivity to pain by decreasing the movement of messages of pain sensation in the nerves. They can cause partial or complete loss of consciousness.
Propofol is used to induce and maintain sleep during anesthesia used during surgery in adults and children 3 years of age and older. It can be used for adults before a medical procedure that can cause discomfort to relax and reduce sensitivity, but without inducing sleep. This is known as conscious sedation. Propofol is also used to decrease the sensitivity and to induce sleep of people treated in an intensive care unit. As a result, the drug alleviates physical stress responses and promotes healing.
This medicine is available under different brand names or in different presentations, or both. A specific brand of this medication may not be available in all forms or approved for all conditions mentioned here. In addition, some forms of this medicine may not be used against all conditions mentioned in this article.
How should this medication be used?
The dose of propofol used depends on the reasons why this drug is given. Your doctor will calculate the appropriate dose based on your body weight. Propofol is given intravenously (in a vein) by an anesthesiologist (a doctor who practices anesthesia).
Propofol should only be given by physicians who have experience in anesthesiology and who are versed in the use of propofol. You must be under constant surveillance and devices for airway maintenance, artificial ventilation, oxygen enrichment and circulatory resuscitation should be immediately available when needed.
There are several factors that can be considered in determining the dose a person needs: weight, health, and other medications. If your doctor has recommended a dose other than those listed here, do not change the way you take the medicine without first consulting it.
It is very important that this medicine be given as directed by your doctor. If you fail to attend an appointment to receive propofol, contact your doctor as soon as possible to schedule another appointment.
Store this medicine at room temperature, away from frost and out of the reach of children.
During the handling of propofol, strict aseptic techniques are still required as this is a disposable injectable product containing no antimicrobial preservatives. The excipient is likely to support the rapid growth of microorganisms. Failure to follow aseptic handling procedures can result in microbial contamination leading to serious infections such as septic shock, which can be life threatening.
In which cases is this medicine not recommended?
Do not use this medicine in the following circumstances:
is allergic to propofol or to any of the ingredients of the medication
pregnancy or breastfeeding;
the person who should receive the drug is 18 years old or younger and is in an intensive care unit;
if the person plans to drive a vehicle or maneuver machinery on the day of the surgery;
the presence of contraindications to sedation or general anesthesia;
the presence of high levels of certain fats in the blood (hypertriglyceridemia).
What are the possible side effects of this medicine?
heat or pain at the injection site
a faster or slower heart rate
nausea or vomiting
low blood pressure
Most of the side effects listed below do not occur very often, but they could cause serious problems if you do not receive medical care.
Check with your doctor as soon as possible if any of the following side effects occur:
Stop taking the medication and seek immediate medical attention if there is an answer such as:
symptoms of a heart attack (eg, chest pain, difficulty breathing, pain along the left arm)
symptoms of low blood sugar
How Propofol come?
Propofol is supplied in a bottle of 10ml