Methadone Hydrochloride

(10 customer reviews)

$300.00$750.00

Methadone Hydrochloride is used to treat addiction to opioids (such as heroin) as part of an approved treatment program. Methadone belongs to a class of drugs known as opioid (narcotic) analgesics. It helps prevent withdrawal symptoms caused by stopping other opioids.

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Description

What is Methadone Hydrochloride?

Methadone Hydrochloride is used to treat addiction to opioids (such as heroin) as part of an approved treatment program. Methadone belongs to a class of drugs known as opioid (narcotic) analgesics. It helps prevent withdrawal symptoms caused by stopping other opioids.

Methadone may also be used to treat severe pain. Do not use methadone to relieve pain that is mild or that will go away in a few days. Methadone is not for occasional (“as needed”) use.

Methadone is available under the following different brand and other names: Methadose, and Dolophine.

Dosage of Methadone Hydrochloride

Opioid-naive patients: 2.5 mg taken orally once every 8-12 hours; titrate slowly with dose increases no more frequent than every 3-5 days

Opioid-tolerant patients

Discontinue all other around-the-clock opioids
Substantial inter-patient variability, see prescribing information for guidance
Opioid-tolerant definition

Use of higher starting doses in patients who are not opioid tolerant may cause fatal respiratory depression
Patients who are opioid tolerant are those receiving, for 1 week or longer, at least 60 mg/day oral morphine, 25 mcg/hour transdermal fentanyl, 30 mg/day oral oxycodone, 8 mg/day oral hydromorphone, 25 mg/day oral oxymorphone, or an equianalgesic dose of another opioid
Limitations of use

Use of the risks of addiction, abuse, and misuse with opioids, even at recommended doses, and because of the greater risks of overdose and death with extended-release opioid formulations, reserve for patients whom alternative treatment options (e.g., non-opioid analgesics or immediate-release opioids) are ineffective, not tolerated, or would be otherwise inadequate to provide sufficient management of pain
Not indicated for acute pain or as an as needed analgesic
Detoxification
20-30 mg taken orally once daily or minimum dosage necessary to suppress withdrawal; may be titrated to 40 mg/day in divided doses and continued for 2-3 days, then decreased 20% daily as tolerated

Dosing Modifications
Renal impairment (CrCl less than 10mL/min): 50-75% of normal dose

Hepatic impairment: Not recommended in severe liver disease

Dosing Considerations
Conversion from oral to parenteral: Parenteral-to-oral ratio, 1:2 (5 mg parenteral = 10 mg taken orally)

To convert to methadone from another opioid, use available conversion factors to obtain estimated dose

Do not abruptly discontinue methadone in a physically dependent patient

Pediatric

Pain (Off-label)
0.7 mg/kg/day orally/subcutaneously/intravenously(IV)/intramuscularly (IM) divided once every 6 hours as needed; not to exceed 10 mg/dose

Opiate Withdrawal (Off-label)
Neonates: 0.05-0.2 mg/kg taken orally once every 12-24 hours; reduce dose by 10-20% per week over 4-6 weeks; adjust tapering on signs and symptoms of withdrawal

Geriatric
Pain
2.5 mg orally or intramuscularly (IM) once every 8-12 hours; titrate slowly with dose increases no more frequent than every 3-5 days

Detoxification
20-30 mg taken orally once daily or minimum dosage necessary to suppress withdrawal; may be titrated to 40 mg/day in divided doses and continued for 2-3 days, then decreased 20% daily as tolerated

Side Effects of Methadone Hydrochloride

Side effects of methadone include:
Agitation
Anticholinergic effects (dry mouth, palpitation, fast heart rate)
Cardiac arrest
Chest pain
Coma
Constipation
Dizziness
Drowsiness
Feeling uneasy
Euphoria
Heart attack (myocardial infarction)
Itching and hives
Lightheadedness or fainting
Mental clouding or depression
Nausea
Nervousness
Respiratory arrest
Respiratory/circulatory depression
Restlessness
Seizures
Severe cardiac arrhythmias
Shock
Slow heart rate
Sweating, flushing, warmness of face/neck/throat
Urinary retention, urinating less than usual
Visual disturbances
Vomiting
Weakness

How Methadone come

Methadone is available in pill form as follow: 10mg and 40mg

Additional information

CHECK VARIATIONS HERE =>

Methadone 10mg (250 tablets), Methadone 10mg (500 tablets), Methadone 10mg (700 tablets), Methadone 40mg (200 tablets), Methadone 40mg (350 tablets), Methadone 40mg (500 tablets)

10 reviews for Methadone Hydrochloride

  1. Wanda M

    Excellent service!

  2. Blaylock

    Great price and timely delivery coupled with with and easy ordering makes using this online medspharma a must.

  3. Mary Kay

    Still have not received my purchase and it has been over a week…(((

  4. Thompson

    Still have not received my purchase and it has been over a week

  5. Candi Owen

    Quick delivery, thankyou đŸ™‚

  6. Ripley Tennessee

    Speedy delivery, would recommend to my friends and family.

  7. Jania Toledo

    Order a third time, always good service. I recommend

  8. Ken Wallace

    Very easy, efficient and fast delivery.

  9. Tabitha Galvan

    Excellent service and rapid delivery.will use again.

  10. Ginny Griffey

    Product as described and delivered next day

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